Before vacuum cleaners, people used to sleep with all kinds of nasties, bed bugs, mites, headlice, fleas (Human fleas and animal fleas), bacteria, sweat, dead skin and all that. Up until the last century people still believed that washing yourself and your clothing was bad for you, so they just went around smelling bad and suffering as a consequence, and even in the 20th century, regular bathing was a relatively rare event, up until it was made popular by movie stars of old...
With cleanliness and hygiene, we are living longer, but being "too clean" is bad for you, cases of allergies and asthma have rocketed over the past few decades simply because people are being too aggressive with their cleaning...